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Heat vs. Cold Therapy: Which is Best for Musculoskeletal Injuries

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4) When to Use Ice Therapy Acute MSK Injuries - i.e., sprains, strains, contusions, etc. Cold therapy has proven to be most beneficial for controlling excessive swelling within the first 6-12 hours post-injury. (1-3) 1-3) Migraine Headaches : Using ice for migraines can provide relief. (5-7) 2006 Oct 1;87(10):1310-7.